The word poliomyelitis originates from the Greek word “polio” meaning “grey” and “myelon” meaning “marrow.” Poliomyelitis is an exclusive human disease transmitted from a patient or a symptom-free carrier through the fecal-oral route. Polio - virus Mye- spinal cord itis - inflammation What type of virus is Polio? Non-enveloped, positive stranded RNA virus Belongs to picornaviridae family in the genus Enterovirus species-Enterovirus C What are the serotypes of Poliovirus? 3 genetically distinct serotypes 1,2, 3 Which type of Polio is maximally associated with Paralytic poliomyelitis? Type1 poliovirus has the greatest propensity for natural poliomyelitis and type 3 poliovirus has a predilection for producing VAPP. How does transmission of Polio virus occur? By feco-oral route and during epidemics via pharyngeal transmission. What is the incubation period of poliomyelitis? Usually 8-12 days with a range of 5 to 35 days What is the pathogenesis of poliomyelitis? After inge